反应详情

Tosyl chloride (8.4 g, 44 mmol) was added to a solution of 3-iodocarbazole (11.7 g, 40 mmol) and grounded KOH (2.7 g, 48 mmol) in 200 mL of acetone. The mixture was refluxed for 3 hours, and then cooled down. It was poured into 1 L of cold water while stirring. After sitting for 30 minutes, the liquid was decanted. The crude product was thus obtained as sticky solid on the beaker wall. About 11 g of pure 3-iodo-9-tosylcarbazole was obtained after recystallization from CH2Cl2/EtOH.

1. temperatureThe mixture was refluxed for 3 hours
2. temperaturecooled down
3. customthe liquid was decanted
4. customThe crude product was thus obtained as sticky solid on the beaker wall