4-Chloroaniline → HCID 24825962, compound

HRID 1514353Notes

Reaction equation

HRID 1514353 reaction equation
Cl[C:2]1[N:7]=[C:6](Cl)[CH:5]=[CH:4][N:3]=1.[Cl:9][C:10]1[CH:16]=[CH:15][C:13]([NH2:14])=[CH:12][CH:11]=1.[N+:17]([C:20]1[CH:28]=[C:27]2[C:23]([CH:24]=[N:25][NH:26]2)=[CH:22][CH:21]=1)([O-:19])=[O:18]>>[Cl:9][C:10]1[CH:16]=[CH:15][C:13]([NH:14][C:6]2[CH:5]=[CH:4][N:3]=[C:2]([N:25]3[CH:24]=[C:23]4[C:27]([CH:28]=[C:20]([N+:17]([O-:19])=[O:18])[CH:21]=[CH:22]4)=[N:26]3)[N:7]=2)=[CH:12][CH:11]=1

Participants

4

Reactant 3

HCID 78124-ChloroanilineHCID 242396-NitroindazoleHCID 775312,4-Dichloropyrimidine

Product 1

HCID 24825962HCID 24825962, compound

Procedure

Was prepared according to Method A from 2,4-dichloropyrimidine, 4-chloroaniline and 6-nitroindazole. LC-ESI-HRMS of [M+H]+ shows 367.0717 Da. Calc. 367.071027 Da, dev. 1.8 ppm.

Workup

  1. customWas prepared

Sources & evidence

ORD record
ord-e283c575f68c40ceb9b7f5adf0bdebc5
Source dataset
uspto-grants-2012_07
Patent number
US08222262B2

Reaction notes

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