4-Chloroaniline → HCID 24825965, compound

HRID 1514360Notes

Reaction equation

HRID 1514360 reaction equation
F[C:2]1[CH:7]=[CH:6][CH:5]=[C:4](F)[N:3]=1.[Cl:9][C:10]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[NH:12][N:11]=1.[Cl:19][C:20]1[CH:26]=[CH:25][C:23]([NH2:24])=[CH:22][CH:21]=1>>[Cl:9][C:10]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[N:12]([C:4]2[N:3]=[C:2]([NH:24][C:23]3[CH:25]=[CH:26][C:20]([Cl:19])=[CH:21][CH:22]=3)[CH:7]=[CH:6][CH:5]=2)[N:11]=1

Participants

4

Reactant 3

HCID 78124-ChloroanilineHCID 739342,6-DifluoropyridineHCID 958943-Chloro-1H-indazole

Product 1

HCID 24825965HCID 24825965, compound

Procedure

Was prepared according to Method C from 2,6-difluoropyridine, 3-chloroindazole and 4-chloroaniline. LC-ESI-HRMS of [M+H]+ shows 355.0528 Da. Calc. 355.051727 Da, dev. 3 ppm.

Workup

  1. customWas prepared

Sources & evidence

ORD record
ord-2bbcaf4a53b945e6a431cea91ee95c3e
Source dataset
uspto-grants-2012_07
Patent number
US08222262B2

Reaction notes

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