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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1514448Generated: November 4, 2026

Hydrochloric Acid → HCID 86640063, compound

https://huagongshe.com/reaction/1514448

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant1,4-DioxaneHCID 31275—
ReactantHCID 24752776HCID 24752776—
ProductHCID 86640063HCID 86640063—

Reaction Steps

4-(2,2-Difluoro-1,3-benzodioxol-4-yl)-1-{4-[(1S,5R)-1-(4-trifluoromethyl-phenyl)-3-aza-bicyclo[3.1.0]hex-3-yl]-butyl}-1H-pyrimidin-2-one was treated with 4N HCl in dioxane (1 eq), to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08222266B2
Source datasetuspto-grants-2012_07
ORD IDord-ca32ee66a0f54df39bbf2389a8d5b218
Source noteuspto-grants-2012_07