HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine → HCID 46929240, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | HCID 66718204 | HCID 66718204 | — |
| Product | HCID 46929240 | HCID 46929240 | 69% |
Reaction Steps
As described in example 43h, 6-(5-hydroxymethyl-3-pyridin-2-yl-isoxazol-4-ylmethoxy)-nicotinic acid (881 mg, 2.7 mmol) was converted, using morpholine instead of thiomorpholine 1,1-dioxide, to the title compound (738 mg, 69%) which was obtained as a white foam. MS: m/e=397.3 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08222246B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-9a51208dbe174e5dbfc9dd35ba062b4a |
| Source note | uspto-grants-2012_07 |