反应详情

A suspension of the above 4-amino-3-nitro-N-quinolin-2-yl-benzamide (5 g, 16.2 mmol) in EtOH (50 mL) was hydrogenated at one atm over PtO2 (250 mg) for 4 h (the suspension will become a clear when the reaction is complete). The catalyst was filtered through Celite and washed with EtOH. The solvent was removed under reduced pressure to give 3,4-diamino-N-quinolin-2-yl-benzamide as a red solid.

1. filtrationThe catalyst was filtered through Celite
2. washwashed with EtOH
3. customThe solvent was removed under reduced pressure