HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-amino-N-(4-tert-butylphenyl)-3-nitrobenzamide → 3,4-diamino-N-(4-tert-butylphenyl)-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-amino-N-(4-tert-butylphenyl)-3-nitrobenzamide | HCID 8779856 | — |
| Catalyst | Platinum | HCID 23939 | — |
| Solvent | Ethanol ethylacetate | HCID 21584252 | — |
| Product | 3,4-diamino-N-(4-tert-butylphenyl)-benzamide | HCID 66966111 | — |
Reaction Steps
A mixture of 4-amino-N-(4-tert-butylphenyl)-3-nitrobenzamide from the previous step and 100 mg of 5% platinum on carbon in 50 mL of 1:1 ethyl acetate/ethanol was reduced under a hydrogen balloon. The reaction was filtered through Celite to remove catalyst and the solvent was removed under reduced pressure to afford 3,4-diamino-N-(4-tert-butylphenyl)-benzamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08222248B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-fb2cdefe1a4e4388b259a9679c5c2a4f |
| Source note | uspto-grants-2012_07 |