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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1515043Generated: October 26, 2026

3,4-diamino-N-(6-trifluoromethylpyridin-3-yl)-benzamide → HCID 178424983, compound

https://huagongshe.com/reaction/1515043

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-diamino-N-(6-trifluoromethylpyridin-3-yl)-benzamideHCID 66965681—
ReactantMethyl 3-(4-formyl-3,5-dimethylphenyl)-2,2-dimethylpropanoateHCID 86632822—
ProductHCID 178424983HCID 178424983—

Reaction Steps

The title compound was prepared from 3,4-diamino-N-(6-trifluoromethylpyridin-3-yl)-benzamide (from Example 6-36) and 3-(4-formyl-3,5-dimethylphenyl)-2,2-dimethylpropionic acid methyl ester analogous to Example 6-29. 1N NMR (400 MHz, MeOD): δ 9.20 (s, 1H), 8.68 (d, 1H), 8.43 (s, 1H), 8.10 (d, 1H), 7.98 (d, 1H), 7.85 (d, 1H), 7.19 (s, 2H), 3.00 (s, 2H), 2.27 (s, 6H), 1.29 (s, 6H). MS (m/z) 511.2 (M+1); Retention time: 1.20 min (Method 10).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08222248B2
Source datasetuspto-grants-2012_07
ORD IDord-8c498e45672e436b92c00594e65af5a4
Source noteuspto-grants-2012_07