Potassium Carbonate → HCID 66937650, compound

Participants

Reaction Steps

The compound (0.027 mmol, 10 mg) obtained in (1) above was dissolved in methanol, to which potassium carbonate (0.015 mmol, 2.05 mg) was added at 0° C., and the resulting solution was stirred for 1 hour. After the disappearance of the starting materials was confirmed by thin-layer chromatography, a saturated aqueous ammonium chloride solution was added to the reaction solution to terminate the reaction. Then, extraction was performed with methylene chloride, the obtained organic layer was dried over sodium sulfate, and the solvents were evaporated under reduced pressure. The residue was purified by silica gel column chromatography, and the title compound (0.019 mmol, 6.2 mg) was obtained in a 72% yield.

Provenance & Evidence