反应详情

17A was prepared in a procedure similar to that of 13A using 5-iminoisoindoline-1,3-dione, 3,4-dimethoxyphenylboronic acid and glyoxylic acid monohydrate. Yield: 88%. 1H NMR (400 MHz, Methanol-d4) δ ppm 3.82 (s, 3H) 3.83 (s, 3H) 5.17 (s, 1H) 6.90 (dd, J=8.35, 2.20 Hz, 1H) 6.95 (d, J=7.91 Hz, 1H) 6.99 (d, J=2.20 Hz, 1H) 7.07-7.10 (m, 1H) 7.13 (d, J=2.20 Hz, 1H) 7.50 (d, J=8.35 Hz, 1H), LCMS: 366 (M+1).