HRID1515518

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID15620607

Oxoacetic acid--water (1/1)

C2H4O4

HCID16782100

3-Amino-4-fluorobenzamide

C7H7FN2O

HCID23005377

(4-Chloro-3-methoxyphenyl)boronic acid

C7H8BClO3

结构：COc1ccc(C(Nc2cccc(C(N)=O)c2)C(=O)O)cc1OC

HCID59838034

未命名化合物

PRODUCTS

生成物

结构：COc1cc(C(Nc2cc(C(N)=O)ccc2F)C(=O)O)ccc1Cl

HCID59479421

未命名化合物

收率 37%

PROCEDURE

实验过程

25B was prepared in a procedure similar to that of 1A using 25A, 19B and glyoxylic acid monohydrate. Yield: 37%. 1H NMR (400 MHz, Methanol-d4) δ ppm 3.88 (s, 3H) 5.21 (s, 1H) 7.03-7.12 (m, 3H) 7.13-7.19 (m, 1H) 7.25 (d, J=1.76 Hz, 1H) 7.33 (d, J=7.91 Hz, 1H), LCMS: 353 (M+1).