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HRID1515526

反应详情

EQUATION

反应方程式

HRID 1515526 的结构方程式

REACTANTS

反应物

4
结构：NC(=O)c1cc(N)ccc1F
HCID2778899

5-amino-2-fluorobenzamide

C7H7FN2O

结构：O.O=CC(=O)O
HCID15620607

Oxoacetic acid--water (1/1)

C2H4O4

结构：COc1cc(B(O)O)ccc1F
HCID44558185

(4-Fluoro-3-methoxyphenyl)boronic acid

C7H8BFO3

结构：COc1ccc(C(Nc2cccc(C(N)=O)c2)C(=O)O)cc1OC
HCID59838034

未命名化合物

PRODUCTS

生成物

1
结构：COc1cc(C(Nc2ccc(F)c(C(N)=O)c2)C(=O)O)ccc1F
HCID59479452

未命名化合物

收率 43%

PROCEDURE

实验过程

39A was prepared in a procedure similar to that of 1A using 3-amino-6-fluorobenzamide, 7C and glyoxylic acid monohydrate. Yield: 43%. 1H NMR (400 MHz, Methanol-d4) δ ppm 3.85 (s, 3H) 5.05 (s, 1H) 6.75-6.82 (m, 1H) 6.92-6.97 (m, 1H) 7.03-7.08 (m, 3H) 7.24-7.29 (m, 1H), LCMS: 337 (M+1).