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HRID1515570

反应详情

EQUATION

反应方程式

HRID 1515570 的结构方程式

REACTANTS

反应物

4
结构：NC(=O)c1cncc(N)c1
HCID173747

3-Pyridinecarboxamide, 5-amino-

C6H7N3O

结构：COc1ccc(B(O)O)cc1OC
HCID2734702

3,4-Dimethoxyphenylboronic acid

C8H11BO4

结构：O.O=CC(=O)O
HCID15620607

Oxoacetic acid--water (1/1)

C2H4O4

结构：COc1ccc(C(Nc2ccc(F)c(C(N)=O)c2)C(=O)O)cc1OC
HCID59479392

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccc(C(Nc2cncc(C(N)=O)c2)C(=O)O)cc1OC
HCID59479403

未命名化合物

收率 63%

PROCEDURE

实验过程

97C was prepared in a procedure similar to that of 13A using 97B, 3,4-dimethoxyphenylboronic acid and glyoxylic acid monohydrate. Yield: 63%. 1H NMR (400 MHz, Methanol-d4) δ ppm 3.82 (s, 3H) 3.84 (s, 3H) 5.28 (s, 1H) 6.97 (d, J=8.35 Hz, 1H) 7.08 (s, 1H) 7.13 (d, J=2.20 Hz, 1H) 8.14 (s, 2H) 8.38 (s, 1H); LCMS: 331 (M+1).