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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 15161Generated: October 31, 2026

Hydrochloric Acid → 2-(Hydroxymethyl)-5-mercapto-4(1h)-pyridinol hydrochloride salt

https://huagongshe.com/reaction/15161

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant{5-[(1,1-Dimethylethyl)thio]-4-oxo-1,4-dihydro-2-pyridinyl}methyl acetateHCID 67526579—
Product2-(Hydroxymethyl)-5-mercapto-4(1h)-pyridinol hydrochloride saltHCID 86614153—

Reaction Conditions

Temperature80 °C

Reaction Steps

A mixture of {5-[(1,1-dimethylethyl)thio]-4-oxo-1,4-dihydro-2-pyridinyl}methyl acetate (240 mg, 0.94 mmol) and concentrated hydrochloric acid (2 ml) was heated to 80° C. overnight. The solvent was evaporated affording a pale yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07732460B2
Source datasetuspto-grants-2010_06
ORD IDord-9a5726d044784afe8533dfb5fa5b7ab4
Source noteuspto-grants-2010_06