Formaldehyde → 4-[4-(4-Ethyl-5-fluoro-2-hydroxyphenoxy)-3-fluorobenzoyl]-1-(morpholinomethyl)piperazin-2-one
Reaction equation
[CH2:1]=[O:2].[CH2:3]1[CH2:4][O:5][CH2:6][CH2:7][NH:8]1.[CH2:9]([CH3:10])[c:11]1[cH:12][c:13]([OH:35])[c:14]([O:15][c:16]2[c:17]([F:31])[cH:18][c:19]([C:20](=[O:21])[N:22]3[CH2:23][C:24](=[O:28])[NH:25][CH2:26][CH2:27]3)[cH:29][cH:30]2)[cH:32][c:33]1[F:34].[CH3:36][CH2:37][O:38][C:39](=[O:40])[CH3:41].[CH3:42][OH:43].[OH2:44].[OH2:45]>>[CH2:3]1[CH2:4][O:5][CH2:6][CH2:7][N:8]1[CH2:36][N:25]1[C:24](=[O:28])[CH2:23][N:22]([C:20]([c:19]2[cH:18][c:17]([F:31])[c:16]([O:15][c:14]3[c:13]([OH:35])[cH:12][c:11]([CH2:9][CH3:10])[c:33]([F:34])[cH:32]3)[cH:30][cH:29]2)=[O:21])[CH2:27][CH2:26]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-93a924ca720e46488f1c7f3ca0f87d0f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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