反应详情

As described for example 10a, 6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-pyridazine-3-carboxylic acid methyl ester (960 mg, 2.95 mmol) was converted, instead of 6-(3-butyl-5-methyl-isoxazol-4-ylmethoxy)-nicotinic acid methyl ester, to the title compound (415 mg, 45%) which was obtained as a white solid. MS: m/e=310.1 [M−H]−.