Acetic Anhydride → HCID 16748464, compound

Participants

Reaction Conditions

Reaction Steps

To a suspension of 4-[6-(4-trifluoromethyl-cyclohex-1-enyl)-pyrimidin-4-yloxy]-benzothiazol-2-ylamine, Example 1(e), (85 mg, 0.22 mmol) in toluene was added acetic anhydride (82 μL, 0.86 mmol). The mixture was heated at 90° C. with stirring for 1 h. The reaction mixture was allowed to cool to room temperature and evaporated in vacuo to give the title compound as a white solid. MS (ESI, pos. ion.) m/z: 435 (M+1).

Provenance & Evidence