Sulfuric Acid → HCID 25267402, compound

HRID 1516395Notes

Reaction equation

HRID 1516395 reaction equation
S(=O)(=O)(O)O.[Cl:6][C:7]1[CH:8]=[CH:9][C:10]([NH:13][C:14]([C:16]2[CH:21]=[C:20]([Cl:22])[CH:19]=[CH:18][C:17]=2[NH:23][C:24]([C:26]2[CH:31]=[CH:30][C:29]([S:32]([CH3:45])(=[N:34]C(OCC3C=CC=CC=3)=O)=[O:33])=[CH:28][CH:27]=2)=[O:25])=[O:15])=[N:11][CH:12]=1.C(=O)([O-])[O-].[K+].[K+]>O>[Cl:6][C:7]1[CH:8]=[CH:9][C:10]([NH:13][C:14]([C:16]2[CH:21]=[C:20]([Cl:22])[CH:19]=[CH:18][C:17]=2[NH:23][C:24]([C:26]2[CH:31]=[CH:30][C:29]([S:32]([CH3:45])(=[NH:34])=[O:33])=[CH:28][CH:27]=2)=[O:25])=[O:15])=[N:11][CH:12]=1

Participants

5

Reactant 3

HCID 1118Sulfuric AcidHCID 11430Potassium CarbonateHCID 71540682HCID 71540682, compound

Product 1

HCID 25267402HCID 25267402, compoundYield 94.4%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Sulfuric acid (50 mL) was cooled to 0-5° C. To this was added product of step 7 (10 g, 0.016 mol) and reaction mixture was stirred at same temperature for 15-20 min. Above reaction mixture was slowly poured in chilled water and basified using aqueous potassium carbonate solution. Precipitated product was filtered and washed with water. Drying afforded 7 g of titled compound in 90% yield.

Workup

  1. additionTo this was added
  2. customAbove reaction mixture
  3. filtrationPrecipitated product was filtered
  4. washwashed with water
  5. customDrying

Sources & evidence

ORD record
ord-183f01102a3f4a89ba6f9b05855b180f
Source dataset
uspto-grants-2012_07
Patent number
US08227492B2

Reaction notes

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