Iodoethane → HCID 25268453, compound

HRID 1516400Notes

Reaction equation

HRID 1516400 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([NH:8][C:9]([C:11]2[CH:16]=[C:15]([Cl:17])[CH:14]=[CH:13][C:12]=2[NH:18][C:19]([C:21]2[CH:26]=[CH:25][C:24]([S:27]([CH3:38])(=[N:29][C:30]([CH:32]3[CH2:37][CH2:36][NH:35][CH2:34][CH2:33]3)=[O:31])=[O:28])=[CH:23][CH:22]=2)=[O:20])=[O:10])=[N:6][CH:7]=1.[CH2:39](I)[CH3:40]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([NH:8][C:9]([C:11]2[CH:16]=[C:15]([Cl:17])[CH:14]=[CH:13][C:12]=2[NH:18][C:19]([C:21]2[CH:22]=[CH:23][C:24]([S:27]([CH3:38])(=[N:29][C:30]([CH:32]3[CH2:37][CH2:36][N:35]([CH2:39][CH3:40])[CH2:34][CH2:33]3)=[O:31])=[O:28])=[CH:25][CH:26]=2)=[O:20])=[O:10])=[N:6][CH:7]=1

Participants

3

Reactant 2

HCID 6340IodoethaneHCID 25268097HCID 25268097, compound

Product 1

HCID 25268453HCID 25268453, compoundYield 71%

Procedure

Product of Example 25 was ethylated using standard N-alkylating procedure with ethyl iodide to give titled compound in 71% yield.

Sources & evidence

ORD record
ord-98bac83af5fc4f1092fbfce546ece838
Source dataset
uspto-grants-2012_07
Patent number
US08227492B2

Reaction notes

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