Hydrochloric Acid → HCID 25271233, compound

Participants

Reaction Steps

To a stirred solution of S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-methyl-N-(2-diethylamino-acetyl)sulfoximide (200 mg,0.3478 mmol) in DCM (5mL) was added 12% ethereal hydrochloric acid solution (115 mg,0.3826 mmol) at 10-15° C. After one hour, solvent was concentrated and product was stirred in ether. Filteration afforded 90 mg of desired product in 42% yield.

Provenance & Evidence