反应详情

Compound 2 (25 g, 126.8 mmol) was solved in diethyl aniline (150 mL, 937.7 mmol) and the resulting solution was refluxed for 48 h. The crude was evaporated in vacuo and the residue was purified by column chromatography, eluted at 10% ethyl acetate/hexane. Fractions were collected to obtain the desired compound 3 (15 g, yield 60%).

1. temperaturethe resulting solution was refluxed for 48 h
2. customThe crude was evaporated in vacuo
3. customthe residue was purified by column chromatography
4. washeluted at 10% ethyl acetate/hexane
5. customFractions were collected