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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1516546Generated: October 27, 2026

2,3-Dihydrobenzo(b)furan-5-carboxylic acid → 2,3-Dihydro-benzofuran-5-carboxylic acid {2-methyl-4-[3-(2-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-phenyl}-amide

https://huagongshe.com/reaction/1516546

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-Dihydrobenzo(b)furan-5-carboxylic acidHCID 676583—
Reactant2-Methyl-4-[3-(2-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-phenylamineHCID 68467642—
Product2,3-Dihydro-benzofuran-5-carboxylic acid {2-methyl-4-[3-(2-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-phenyl}-amideHCID 25263719—

Reaction Steps

The title compound was prepared in a manner substantially the same as Example 1 by coupling 2-methyl-4-[3-(2-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-phenylamine with 2,3-dihydro-benzofuran-5-carboxylic acid. MS: 420.3 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08227504B2
Source datasetuspto-grants-2012_07
ORD IDord-a702b857bf38477999a1b30b3fa7192e
Source noteuspto-grants-2012_07