4-(1-Imidazolyl)benzoic Acid → HCID 25229620, compound

HRID 1516550Notes

Reaction equation

HRID 1516550 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([CH2:13][N:14]3[CH2:18][CH2:17][CH2:16][CH:15]3[CH3:19])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH2:20].[N:21]1([C:26]2[CH:34]=[CH:33][C:29]([C:30](O)=[O:31])=[CH:28][CH:27]=2)[CH:25]=[CH:24][N:23]=[CH:22]1>>[N:21]1([C:26]2[CH:27]=[CH:28][C:29]([C:30]([NH:20][C:3]3[CH:4]=[CH:5][C:6]([N:8]4[CH2:12][CH2:11][CH:10]([CH2:13][N:14]5[CH2:18][CH2:17][CH2:16][CH:15]5[CH3:19])[CH2:9]4)=[CH:7][C:2]=3[CH3:1])=[O:31])=[CH:33][CH:34]=2)[CH:25]=[CH:24][N:23]=[CH:22]1

Participants

3

Reactant 2

HCID 7365294-(1-Imidazolyl)benzoic AcidHCID 684676422-Methyl-4-[3-(2-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-phenylamine

Product 1

HCID 25229620HCID 25229620, compound

Procedure

The title compound was prepared in a manner substantially the same as Example 1 by coupling 2-methyl-4-[3-(2-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-phenylamine with 4-imidazol-1-yl-benzoic acid. MS: 444.3 (M+H).

Sources & evidence

ORD record
ord-6b2d29136e5c43b2af757618369bfdcc
Source dataset
uspto-grants-2012_07
Patent number
US08227504B2

Reaction notes

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