Succinic anhydride → 7-Bromo-1,2,3,4-tetrahydronaphthalen-1-one

HRID 1517021Notes

Reaction equation

[Br:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:8]1(=O)O[C:11](=[O:12])[CH2:10][CH2:9]1>>[Br:1][C:2]1[CH:7]=[C:6]2[C:5]([CH2:8][CH2:9][CH2:10][C:11]2=[O:12])=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 7922Succinic anhydride

HCID 7961Bromobenzene

Product 1

HCID 2527317-Bromo-1,2,3,4-tetrahydronaphthalen-1-one

Procedure

7-Bromo-3,4-dihydronaphthalen-1-one was prepared from bromobenzene and succinic anhydride as described in Example 64 (Steps A to C).

Sources & evidence

ORD record: ord-370e0d3422a4480e928ae4a706476fbc
Source dataset: uspto-grants-2012_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08227486B2

Reaction notes

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