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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1517404Generated: November 2, 2026

Morpholine → 6-Chloro-4-(morpholin-4-yl)pyrido[3,2-d]pyrimidine

https://huagongshe.com/reaction/1517404

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
Reactant4,6-Dichloropyrido[3,2-d]pyrimidineHCID 10584165—
Product6-Chloro-4-(morpholin-4-yl)pyrido[3,2-d]pyrimidineHCID 7140769871%

Reaction Steps

The title compound was synthesized in 71% yield from 4,6-dichloro-pyrido[3,2-d]pyrimidine and morpholine by the procedure of example 65, and was characterized by its mass spectrum as follows: MS (m/z): 251.1 ([M+H]+, 100).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08232278B2
Source datasetuspto-grants-2012_07
ORD IDord-40e4627880354fa1bc8a8fe93a31816c
Source noteuspto-grants-2012_07