HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glycol monoethyl ether → N-[6-Chloro-4-(2-ethoxyethoxy)pyrido[3,2-d]pyrimidin-2-yl]acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glycol monoethyl ether | HCID 8076 | — |
| Reactant | N-(6-Chloro-4-oxo-1,4-dihydropyrido[3,2-d]pyrimidin-2-yl)acetamide | HCID 135978119 | — |
| Product | N-[6-Chloro-4-(2-ethoxyethoxy)pyrido[3,2-d]pyrimidin-2-yl]acetamide | HCID 71428444 | 48.3% |
Reaction Steps
4 mmol 2-acetamido-6-chloro-pyrido[3,2-d]pyrimidin-4(3H)-one (0.954 g) was reacted with 6 mmol 2-ethoxyethanol (0.54 g) yielding the pure title compound (0.6 g, yield: 48%) which was characterised as follows:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08232278B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-150ad383a94b4cf790140d5b3177662f |
| Source note | uspto-grants-2012_07 |