HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxyethanol → 6-(4-Fluorophenyl)-4-(2-methoxyethoxy)pyrido[3,2-d]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxyethanol | HCID 8019 | — |
| Reactant | 6-(4-Fluorophenyl)-4-phenoxypyrido[3,2-d]pyrimidine | HCID 57698347 | — |
| Reactant | 4-Chloro-6-(4-fluorophenyl)pyrido[3,2-d]pyrimidine | HCID 57906756 | — |
| Product | 6-(4-Fluorophenyl)-4-(2-methoxyethoxy)pyrido[3,2-d]pyrimidine | HCID 57698333 | 78% |
Reaction Steps
was synthesized from 4-chloro-6-(4-fluorophenyl)-pyrido[3,2-d]pyrimidine and 2-methoxyethanol in 78% yield, using the procedure described for the synthesis of 4-phenoxy-6-(4-fluorophenyl)-pyrido[3,2-d]pyrimidine The mass spectrum characterising data is as follows: MS (m/z): 300 ([M+H]+, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08232278B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-84ebff27d16d4b87a5e78d7c8d1de6fe |
| Source note | uspto-grants-2012_07 |