HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Fluorophenylboronic acid → 3-Amino-6-(3-fluorophenyl)pyridine-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Fluorophenylboronic acid | HCID 2733986 | — |
| Reactant | 3-Amino-6-chloropyridine-2-carboxamide | HCID 10749704 | — |
| Reactant | 3-Amino-6-(4-fluorophenyl)picolinamide | HCID 59647906 | — |
| Product | 3-Amino-6-(3-fluorophenyl)pyridine-2-carboxamide | HCID 57698342 | 92% |
Reaction Steps
was synthesized from 3-amino-6-chloropyridine-2-carboxylic acid amide and 3-fluorophenylboronic acid in 92% yield as a white solid, using the procedure described for the synthesis of 3-amino-6-(4-fluorophenyl)-pyridine-2-carboxylic acid amide. The mass spectrum was as follows: MS (m/z): 232 ([M+H]+, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08232278B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-bf4635dbfe234b77b14b1db52eea5732 |
| Source note | uspto-grants-2012_07 |