HRID1517658

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID887

Methanol

CH4O

反应SMILES：CC1CN(C2CC2)CCN1[C@H]1CC[C@@H](N(Cc2ccccc2)Cc2ccccc2)CC1

HCID178429835

未命名化合物

PRODUCTS

产物

反应SMILES：N[C@H]1CC[C@@H](N2CCN(CC3CC3)CC2)CC1

HCID178511578

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID23938

Palladium

PROCEDURE

实验过程

8.5 g (20 mmol) cis-dibenzyl-[4-(4-cyclopropyl methyl-piperazin-1-yl)-cyclohexyl]-amine are dissolved in 170 ml of methanol and hydrogenated on 1.7 g Pd/C (10%) at 30-50° C. The solvent is eliminated in vacuo and the residue is crystallised from ethanol and conc. HCl. Yield: 4.4 g

WORKUP

后处理

customthe residue is crystallised from ethanol and conc. HCl