HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 178511578, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | HCID 178429835 | HCID 178429835 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | HCID 178511578 | HCID 178511578 | — |
Reaction Steps
8.5 g (20 mmol) cis-dibenzyl-[4-(4-cyclopropyl methyl-piperazin-1-yl)-cyclohexyl]-amine are dissolved in 170 ml of methanol and hydrogenated on 1.7 g Pd/C (10%) at 30-50° C. The solvent is eliminated in vacuo and the residue is crystallised from ethanol and conc. HCl. Yield: 4.4 g
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08232286B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-1e0774b1c59742c296eaf46a5c6639bf |
| Source note | uspto-grants-2012_07 |