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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1517843Generated: November 3, 2026

Succinic Acid → HCID 66669792, compound

https://huagongshe.com/reaction/1517843

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSuccinic AcidHCID 1110—
Reactant(R)-1-(4-(3-fluoro-4-(7-methoxyquinolin-4-yloxy)phenylcarbamoyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydropyrazol-1-yl)propan-2-yl 2-(methylamino)acetateHCID 46937772—
ProductHCID 66669792HCID 66669792—

Reaction Steps

The title compound was prepared according to the procedure described in Example 39 step 3 by using (R)-1-(4-(4-(7-methoxyquinolin-4-yloxy)-3-fluorophenylcarbamoyl)-2,3-dihydro-5-methyl-3-oxo-2-phenylpyrazol-1-yl)propan-2-yl-2-(methylamino)acetate (82.3 mg, 0.134 mmol) and succinic acid (31.6 mg, 0.268 mmol, Guangdong Chemical Reagent Engineering-technological Research and Development Center). The title compound was abtained as a pale yellow solid (70.5 mg, 72%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08232294B2
Source datasetuspto-grants-2012_07
ORD IDord-38c50877f35a4f22bb12fcd7f7965378
Source noteuspto-grants-2012_07