Sodium Iodide → HCID 69047404, compound

HRID 1517918Notes

Reaction equation

HRID 1517918 reaction equation
[P:1]([O:20][CH2:21][CH2:22][NH:23][C:24]([C:37]1[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=1)([C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1)[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1)([O:11][CH2:12][CH2:13][O:14][C:15](=[O:19])[C:16]([CH3:18])=[CH2:17])([O:3]CC1C=CC=CC=1)=[O:2].[I-].[Na+:44]>CC(C)=O>[P:1]([O-:3])([O:20][CH2:21][CH2:22][NH:23][C:24]([C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1)([C:37]1[CH:38]=[CH:39][CH:40]=[CH:41][CH:42]=1)[C:31]1[CH:32]=[CH:33][CH:34]=[CH:35][CH:36]=1)([O:11][CH2:12][CH2:13][O:14][C:15](=[O:19])[C:16]([CH3:18])=[CH2:17])=[O:2].[Na+:44]

Participants

4

Reactant 2

HCID 5238Sodium IodideHCID 69049138HCID 69049138, compound

Product 1

HCID 69047404HCID 69047404, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

Specifically, the desired zwitterionic monomer represented by the Chemical Formula 16 can be obtained as follows. 2-Iodoethyl methacrylate and silver benzyl 2-(tritylamino)ethyl phosphate are refluxed in toluene, and thus benzyl 2-(methacryloyloxy)ethyl 2-(tritylamino)ethyl phosphate can be obtained. Next, benzyl 2-(methacryloyloxy)ethyl 2-(tritylamino)ethyl phosphate and sodium iodide are refluxed in acetone, and thus sodium 2-(methacryloyloxy)ethyl 2-(tritylamino)ethyl phosphate can be obtained. Next, sodium 2-(methacryloyloxy)ethyl 2-(tritylamino)ethyl phosphate is heated in 90% acetic acid under stirring, and thus the desired zwitterionic monomer represented by the Chemical Formula 16 can be obtained.

Sources & evidence

ORD record
ord-47613f2102bf4faeb40df2c8dbefd85b
Source dataset
uspto-grants-2012_07
Patent number
US08232344B2

Reaction notes

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