1-Chloro-3-methoxy-5-nitrobenzene → 3-Chloro-5-nitrophenol

HRID 1517949노트

반응식

HRID 1517949 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([O:11]C)[CH:5]=[C:6]([N+:8]([O-:10])=[O:9])[CH:7]=1.Cl.[NH+]1C=CC=CC=1>O>[Cl:1][C:2]1[CH:3]=[C:4]([OH:11])[CH:5]=[C:6]([N+:8]([O-:10])=[O:9])[CH:7]=1

참가 물질

4

반응물 2

HCID 140260501-Chloro-3-methoxy-5-nitrobenzeneHCID 21584435Pyridinium hydrochloride

생성물 1

HCID 106758153-Chloro-5-nitrophenol

시약·촉매·용매 1

HCID 962Water용매

반응 조건

온도
200 °C

실험 절차

1.65 g 3-chloro-5-nitroanisole are combined with 20.3 g pyridinium hydrochloride and heated to 200° C. for 1 hour. Then the mixture is left overnight to come up to ambient temperature, 200 ml of water are added, the precipitated solid is suction filtered and dried in vacuo.

후처리

  1. customto come up to ambient temperature
  2. filtrationfiltered
  3. customdried in vacuo

출처 및 근거

ORD 기록
ord-e4202f6d93384bbeba6d430408847eb9
출처 데이터셋
uspto-grants-2012_07
특허 번호
US08232312B2

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