HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1517949Generated: October 26, 2026
1-Chloro-3-methoxy-5-nitrobenzene → 3-Chloro-5-nitrophenol
https://huagongshe.com/reaction/1517949
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-Chloro-3-methoxy-5-nitrobenzene | HCID 14026050 | — |
| Reactant | Pyridinium hydrochloride | HCID 21584435 | — |
| Solvent | Water | HCID 962 | — |
| Product | 3-Chloro-5-nitrophenol | HCID 10675815 | — |
Reaction Steps
1.65 g 3-chloro-5-nitroanisole are combined with 20.3 g pyridinium hydrochloride and heated to 200° C. for 1 hour. Then the mixture is left overnight to come up to ambient temperature, 200 ml of water are added, the precipitated solid is suction filtered and dried in vacuo.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08232312B2 |
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| Source dataset | uspto-grants-2012_07 |
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| ORD ID | ord-e4202f6d93384bbeba6d430408847eb9 |
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| Source note | uspto-grants-2012_07 |
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