反应详情

温度

100 °C

A mixture of compound 44B (2 g, 8.26 mmol) and phosphoryl trichloride (11.51 mL, 124 mmol) was heated at 100° C. for 2 h and cooled. The reaction mixture was slowly poured onto ice. The precipitate was collected, washed with water and dried to provide the desired product. MS (APCI): m/z 261 (M+H).

1. temperaturecooled
2. additionThe reaction mixture was slowly poured onto ice
3. customThe precipitate was collected
4. washwashed with water
5. customdried