3-Chloro-1-propanol → HCID 118202508, compound

Participants

Reaction Steps

In Scheme 3, Compound (α1) is reacted with hydroxylamine hydrochloride to obtain (E)-1-(2-aminophenyl)ethanone oxime (Compound (a4)). Compound (a4) is reacted with 3-chloropropan-1-ol to obtain (E)-1-(2-aminophenyl)ethanone O-3-hydroxypropyl oxime (Compound (a5)). Compound (a5) is then reacted with p-pivaloyloxybenzenesulfonyl chloride to obtain the compound of formula (I). The following Compound (7) in Preparation Examples 6 was prepared using Scheme 3.

Provenance & Evidence