反应详情

温度

55 °C

Add benzyl bromide (4.3 mL, 36.4 mmol) to a solution of 4-isopropylpyridine (4.8 mL, 36.4 mmol) in acetone (16.3 mL). Stir the reaction mixture at 55° C. overnight. Concentrate the solvent and add diethyl ether. Sonicate the mixture and then decant the solvent. Dry the solid under vacuum to obtain the title compound as a pale yellow waxy solid (11.1 g, 100%). MS (m/z): 212 (M-Br).

1. concentrationConcentrate the solvent
2. additionadd diethyl ether
3. customSonicate the mixture
4. customdecant the solvent
5. customDry the solid under vacuum