Methylparaben → HCID 54575705, compound

HRID 1519249Notes

Reaction equation

HRID 1519249 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([S:8][C:9]2[O:13][C:12]([C:14]3[CH:19]=[CH:18][C:17]([F:20])=[CH:16][CH:15]=3)=[N:11][C:10]=2[CH:21]([OH:23])[CH3:22])=[N:6][CH:7]=1.[C:24]([C:28]1[CH:33]=[CH:32][C:31](O)=[CH:30][CH:29]=1)([O:26][CH3:27])=[O:25]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([S:8][C:9]2[O:13][C:12]([C:14]3[CH:19]=[CH:18][C:17]([F:20])=[CH:16][CH:15]=3)=[N:11][C:10]=2[CH:21]([O:23][C:31]2[CH:32]=[CH:33][C:28]([C:24]([O:26][CH3:27])=[O:25])=[CH:29][CH:30]=2)[CH3:22])=[N:6][CH:7]=1

Participants

3

Reactant 2

HCID 7456MethylparabenHCID 71184068HCID 71184068, compound

Product 1

HCID 54575705HCID 54575705, compound

Procedure

Prepared from 1-{5-[(5-chloropyridin-2-yl)sulfanyl]-2-(4-fluorophenyl)-1,3-oxazol-4-yl}ethanol (INTERMEDIATE B6.1) and 4-carbomethoxyphenol using a similar procedure as described in the preparation of example B2.1. MS: M+H=485.

Workup

  1. customas described in the preparation of example B2.1

Sources & evidence

ORD record
ord-cfb87f78e98b446d871d9724f999447f
Source dataset
uspto-grants-2015_07
Patent number
US09073879B2

Reaction notes

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