Trifluoroacetic acid → HCID 67514674, compound

Participants

Reaction Steps

A solution of tert-butyl 4-[2-(4-cyano-3-methoxyphenyl)ethyl]-3-(trifluoromethyl)piperazine-1-carboxylate (116 mg, 0.282 mmol) in dichloromethane (2 mL) was treated with trifluoroacetic acid (1 mL) and stirred at room temperature for 2 hours. The reaction mixture was concentrated to provide 2-methoxy-4-{2-[2-(trifluoromethyl)piperazin-1-yl]ethyl}benzonitrile. LC-MS (IE, m/z): 314.4 [M+1]+.

Provenance & Evidence