HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2-Oxo-1,2,3,4-tetrahydroquinolin-1-yl)acetic acid → Methyl 4-bromo-2-(2-(2-oxo-3,4-dihydroquinolin-1(2H)-yl)acetamido)thiophene-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2-Oxo-1,2,3,4-tetrahydroquinolin-1-yl)acetic acid | HCID 16784221 | — |
| Reactant | Methyl 2-amino-4-bromothiophene-3-carboxylate | HCID 68754257 | — |
| Product | Methyl 4-bromo-2-(2-(2-oxo-3,4-dihydroquinolin-1(2H)-yl)acetamido)thiophene-3-carboxylate | HCID 68782720 | — |
Reaction Steps
The title compound was prepared from 2-(2-oxo-3,4-dihydroquinolin-1(2H)-yl)acetic acid (447 mg, 2.18 mmol) and methyl 2-amino-4-bromothiophene-3-carboxylate (516 mg, 2.18 mmol) according to protocol A. Retention time (min)=2.528, method [1], MS(ESI) 423.0 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09073891B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-1400d3487e5a4e84a58ae37127f10bfa |
| Source note | uspto-grants-2015_07 |