関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Methyl 2-(4-(3-(piperidin-1-yl)propoxy)phenyl)acetate | HCID 68756457 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | 2-(4-(3-(Piperidin-1-yl)propoxy)phenyl)acetic acid | HCID 44769635 | — |
反応手順
To a stirring mixture of methyl 2-(4-(3-(piperidin-1-yl)propoxy)phenyl)acetate (570 mg) in HOAc (5 mL) was added 6N HCl (10 mL). The reaction mixture was warmed to 80° C. for 2 h. The crude product mixture was concentrated under reduced pressure and directly taken to the next reaction without further purification. Method[1], MS(ESI) 278.1 [M+H], Retention time=0.666 min.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US09073891B2 |
|---|
| 出典データセット | uspto-grants-2015_07 |
|---|
| ORD ID | ord-ca36871f0d1242288ad3b8bb3b39bb41 |
|---|
| 出典メモ | uspto-grants-2015_07 |
|---|
