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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1519949Generated: October 26, 2026

4-Iodophenylacetic acid → Methyl 2-(2-(4-iodophenyl)acetamido)-4-methylthiophene-3-carboxylate

https://huagongshe.com/reaction/1519949

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Iodophenylacetic acidHCID 137214—
ReactantMethyl 2-amino-4-methylthiophene-3-carboxylateHCID 2759773—
ProductMethyl 2-(2-(4-iodophenyl)acetamido)-4-methylthiophene-3-carboxylateHCID 6875559887%

Reaction Steps

The title compound was synthesized in 87% yield according to protocol A from 2-(4-iodophenyl)acetic acid and methyl 2-amino-4-methylthiophene-3-carboxylate. 13C NMR (CDCl3) δ 167.5, 166.6, 149.8, 138.1, 134.8, 133.1, 131.4, 113.0, 112.3, 93.2, 51.5, 43.3, 17.8; MH+ 416.0.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09073891B2
Source datasetuspto-grants-2015_07
ORD IDord-bb2b48de9ee8425589c93989a5fcc7c9
Source noteuspto-grants-2015_07