1-Naphthaleneacetic Acid → Methyl 3-(2-(naphthalen-1-yl)acetamido)thiophene-2-carboxylate

HRID 1519950노트

반응식

HRID 1519950 반응식
[NH2:1][C:2]1[CH:6]=[CH:5][S:4][C:3]=1[C:7]([O:9][CH3:10])=[O:8].[C:11]1([CH2:21][C:22](O)=[O:23])[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH:14]=[CH:13][CH:12]=1>>[C:11]1([CH2:21][C:22]([NH:1][C:2]2[CH:6]=[CH:5][S:4][C:3]=2[C:7]([O:9][CH3:10])=[O:8])=[O:23])[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH:14]=[CH:13][CH:12]=1

참가 물질

3

반응물 2

HCID 68621-Naphthaleneacetic AcidHCID 89652Methyl 3-amino-2-thiophenecarboxylate

생성물 1

HCID 25660569Methyl 3-(2-(naphthalen-1-yl)acetamido)thiophene-2-carboxylate

실험 절차

Methyl 3-(2-(naphthalen-1-yl)acetamido)thiophene-2-carboxylate was prepared from methyl 3-aminothiophene-2-carboxylate (4.30 g, 27.3 mmol) and 2-(naphthalen-1-yl)acetic acid (3.10 g, 27.3 mmol) according to protocol A. Retention time (min)=8.738, method [7], MS(ESI) 326.1 (M+H).

출처 및 근거

ORD 기록
ord-85d3cbb778b242d68a676936a99d5b1e
출처 데이터셋
uspto-grants-2015_07
특허 번호
US09073891B2

반응 노트

불러오는 중…