HRID1519979

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID16784221

(2-Oxo-3,4-dihydroquinolin-1(2H)-yl)acetic acid

C11H11NO3

结构：Nc1ccsc1-c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1

HCID68785933

未命名化合物

PRODUCTS

生成物

结构：O=C(CN1C(=O)CCc2ccccc21)Nc1ccsc1-c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1

HCID68783981

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from 2-(1-trityl-1H-imidazol-4-yl)thiophen-3-amine and 2-(2-oxo-3,4-dihydroquinolin-1(2H)-yl)acetic acid using protocol B (269 mg, 32%). Method [7] Retention time 9.32 min by HPLC (MH+ 595).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-06e9aacfae494738bfd6faff87d66bf6
来源数据集: uspto-grants-2015_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US09073891B2
来源说明: uspto-grants-2015_07

反应 SMILES

[C:1]([N:20]1[CH:24]=[C:23]([C:25]2[S:26][CH:27]=[CH:28][C:29]=2[NH2:30])[N:22]=[CH:21]1)([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[O:31]=[C:32]1[CH2:41][CH2:40][C:39]2[C:34](=[CH:35][CH:36]=[CH:37][CH:38]=2)[N:33]1[CH2:42][C:43](O)=[O:44]>>[O:31]=[C:32]1[CH2:41][CH2:40][C:39]2[C:34](=[CH:35][CH:36]=[CH:37][CH:38]=2)[N:33]1[CH2:42][C:43]([NH:30][C:29]1[CH:28]=[CH:27][S:26][C:25]=1[C:23]1[N:22]=[CH:21][N:20]([C:1]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)([C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=2)[CH:24]=1)=[O:44]