Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 86674813 | HCID 86674813 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 86674814 | HCID 86674814 | — |
Reaction Steps
(S)-tert-Butyl 2-(4-(1-(3-chloropyrazin-2-yl)-1H-pyrazole-3-carboxamido)phenyl)morpholine-4-carboxylate (44 mg, 90.7 μmol) was dissolved in dioxane (0.35 ml) and a solution of HCl in dioxane (340 μl, 1.36 mmol) was added and the reaction mixture was stirred at 60° C. for 90 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09073911B2 |
|---|
| Source dataset | uspto-grants-2015_07 |
|---|
| ORD ID | ord-88e0c76f68f74b619e24ca3272a0be55 |
|---|
| Source note | uspto-grants-2015_07 |
|---|
