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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 152169Generated: October 25, 2026

Tetrahydrofuran → tert-butyl 3-(2-chloro-9-methyl-6-morpholino-9H-purin-8-yl)-3-hydroxypiperidine-1-carboxylate

https://huagongshe.com/reaction/152169

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantN,N,N',N'-TetramethylethylenediamineHCID 8037—
ReactantTert-butyl 3-oxopiperidine-1-carboxylateHCID 2756825—
Reactant2-Chloro-9-methyl-6-(4-morpholinyl)-9H-purineHCID 71500687—
ReactantButyllithiumHCID 178418339—
Producttert-butyl 3-(2-chloro-9-methyl-6-morpholino-9H-purin-8-yl)-3-hydroxypiperidine-1-carboxylateHCID 59605825—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-b0594f04e1aa44a3a04d29a3e344e213
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)