Tetrahydrofuran → tert-butyl 3-(2-chloro-9-methyl-6-morpholino-9H-purin-8-yl)-3-hydroxypiperidine-1-carboxylate
Reaction equation
[C:31]([CH3:32])([CH3:33])([CH3:34])[O:35][C:36](=[O:37])[N:38]1[CH2:39][C:40](=[O:44])[CH2:41][CH2:42][CH2:43]1.[CH2:45]1[O:46][CH2:47][CH2:48][CH2:49]1.[CH3:18][N:19]([CH3:20])[CH2:21][CH2:22][N:23]([CH3:24])[CH3:25].[CH3:26][CH2:27][CH2:28][CH2:29][Li:30].[Cl:1][c:2]1[n:3][c:4]([N:12]2[CH2:13][CH2:14][O:15][CH2:16][CH2:17]2)[c:5]2[n:6][cH:7][n:8]([CH3:11])[c:9]2[n:10]1>>[Cl:1][c:2]1[n:3][c:4]([N:12]2[CH2:13][CH2:14][O:15][CH2:16][CH2:17]2)[c:5]2[n:6][c:7]([C:40]3([OH:44])[CH2:39][N:38]([C:36]([O:35][C:31]([CH3:32])([CH3:33])[CH3:34])=[O:37])[CH2:43][CH2:42][CH2:41]3)[n:8]([CH3:11])[c:9]2[n:10]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-b0594f04e1aa44a3a04d29a3e344e213
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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