Sodium Hydroxide → HCID 90412644, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of Example 309D (3.0 g, 5.61 mmol) in 1,4-dioxane (50 mL) was treated with a solution of sodium hydroxide (0.673 g, 16.83 mmol) in water (10 mL). The resulting mixture was stirred at 80° C. overnight. Most solvent was evaporated. The solids were filtered, washed with water/ethyl acetate/ether, and vacuum oven-dried to give the title compound. MS (ESI+) m/z 395.1 (M+H)+.

Provenance & Evidence