HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Phenoxyphenylboronic acid → HCID 71092775, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Phenoxyphenylboronic acid | HCID 2734377 | — |
| Reactant | trans-1-Boc-4-aminomethyl-3-hydroxypiperidine | HCID 11075229 | — |
| Reactant | 5,6-Dichloro-pyrimidin-4-ylamine | HCID 24219262 | — |
| Product | HCID 71092775 | HCID 71092775 | — |
Reaction Steps
(3S,4S)-4-(((6-amino-5-(4-phenoxyphenyl)pyrimidin-4-yl)amino)methyl)piperidin-3-ol hydrochloride was prepared from 5,6-dichloropyrimidin-4-amine, (3S,4S)-tert-butyl 4-(aminomethyl)-3-hydroxypiperidine-1-carboxylate, and (4-phenoxyphenyl)boronic acid according to general scheme 3 using methods S1, S2, and S3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09073947B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-ccbdb68c53dd4536a4f05a3629dabece |
| Source note | uspto-grants-2015_07 |