Sodium Hydroxide → HCID 68387020, compound

Participants

Reaction Steps

2.80 g (8.80 mmol) of ethyl 3-(3,5-dichlorophenyl)-5-(hydroxymethyl)-4,5-dihydro-1,2-oxazole-5-carboxylate were dissolved in 100 ml of methanol, and a solution of mg (11.4 mmol) of NaOH in 20 ml of water was added. After 18 h of stirring at RT, the solvents were removed under reduced pressure, water and methylene chloride were added and the organic phase was separated off. On acidification of the aqueous phase, the product separated off as a white precipitate, which was filtered off and dried.

Provenance & Evidence